Yeast Krr1p Physically and Functionally Interacts with a Novel Essential Kri1p, and Both Proteins Are Required for 40S Ribosome Biogenesis in the Nucleolus

Using a two-hybrid screening with TOM1, a putative ubiquitin-ligase gene of Saccharomyces cerevisiae, we isolated KRR1, a homologue of human HRB2 (for human immunodeficiency virus type 1 Rev-binding protein 2). To characterize the gene function, we constructed temperature-sensitive krr1 mutants and...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Sasaki, Takeshi, Toh-e, Akio, Kikuchi, Yoshiko
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell and Organelle Structure and Assembly
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86407/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11027267/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.21.7971-7979.2000
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