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A Novel AP-1 Element in the CD95 Ligand Promoter Is Required for Induction of Apoptosis in Hepatocellular Carcinoma Cells upon Treatment with Anticancer Drugs

The CD95 (also called APO-1 or Fas) system plays a major role in the induction of apoptosis in lymphoid and nonlymphoid tissues in response to a variety of extracellular signals, including chemotherapeutic drugs. Here we report that the CD95 ligand (CD95L) is upregulated in hepatoma cells upon treat...

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Detalhes bibliográficos
Main Authors: Eichhorst, Sören T., Müller, Martina, Li-Weber, Min, Schulze-Bergkamen, Henning, Angel, Peter, Krammer, Peter H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86378/
https://ncbi.nlm.nih.gov/pubmed/11003676
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