Functional Conservation of Regulatory Elements in the pdx-1 Gene: PDX-1 and Hepatocyte Nuclear Factor 3β Transcription Factors Mediate β-Cell-Specific Expression

The PDX-1 transcription factor plays a key role in pancreatic development and in the regulation of the insulin gene in the adult β cell. As its functions appear to be similar in humans and mice, we analyzed the functional conservation of homologous sequences important for the maintenance and the cel...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Marshak, Sonya, Benshushan, Etty, Shoshkes, Michal, Havin, Leora, Cerasi, Erol, Melloul, Danielle
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86312/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11003654/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.20.7583-7590.2000
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