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An Intronic Splicing Silencer Causes Skipping of the IIIb Exon of Fibroblast Growth Factor Receptor 2 through Involvement of Polypyrimidine Tract Binding Protein

Alternative splicing of fibroblast growth factor receptor 2 (FGF-R2) transcripts involves the mutually exclusive usage of exons IIIb and IIIc to produce two different receptor isoforms. Appropriate splicing of exon IIIb in rat prostate cancer DT3 cells requires a previously described cis element (IS...

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Udgivet i:Mol Cell Biol
Principais autores: Carstens, Russ P., Wagner, Eric J., Garcia-Blanco, Mariano A.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86292/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982855/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.19.7388-7400.2000
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