C/EBPβ, When Expressed from the C/ebpα Gene Locus, Can Functionally Replace C/EBPα in Liver but Not in Adipose Tissue

Knockout of C/EBPα causes a severe loss of liver function and, subsequently, neonatal lethality in mice. By using a gene replacement approach, we generated a new C/EBPα-null mouse strain in which C/EBPβ, in addition to its own expression, substituted for C/EBPα expression in tissues. The homozygous...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Chen, Shih-Shun, Chen, Jin-Feng, Johnson, Peter F., Muppala, Vijayakumar, Lee, Ying-Hue
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86283/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10982846/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.19.7292-7299.2000
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