Analysis of Genetic Variability within the Immunodominant Epitopes of Envelope gp41 from Human Immunodeficiency Virus Type 1 (HIV-1) Group M and Its Impact on HIV-1 Antibody Detection

The serodiagnosis of human immunodeficiency virus type 1 (HIV-1) infection primarily relies on the detection of antibodies, most of which are directed against the immunodominant regions (IDR) of HIV-1 structural proteins. Among these, the N-terminal region of gp41 contains cluster I (amino acids [aa...

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Autori principali: Dorn, Jonathan, Masciotra, Silvina, Yang, Chunfu, Downing, Robert, Biryahwaho, Benon, Mastro, Timothy D., Nkengasong, John, Pieniazek, Danuta, Rayfield, Mark A., Hu, Dale J., Lal, Renu B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2000
Soggetti:
Virology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC86201/
https://ncbi.nlm.nih.gov/pubmed/10655384
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