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Potentiation of GATA-2 Activity through Interactions with the Promyelocytic Leukemia Protein (PML) and the t(15;17)-Generated PML-Retinoic Acid Receptor α Oncoprotein

The hematopoietically expressed GATA family of transcription factors function as key regulators of blood cell fate. Among these, GATA-2 is implicated in the survival and growth of multipotential progenitors. Here we report that the promyelocytic leukemia protein (PML) can complex with GATA-2 and pot...

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Published in:Mol Cell Biol
Main Authors: Tsuzuki, Shinobu, Towatari, Masayuki, Saito, Hidehiko, Enver, Tariq
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2000
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86102/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938104/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6276-6286.2000
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