The Molecular Chaperone Activity of Simian Virus 40 Large T Antigen Is Required To Disrupt Rb-E2F Family Complexes by an ATP-Dependent Mechanism

The simian virus 40 large T antigen (T antigen) inactivates tumor suppressor proteins and therefore has been used in numerous studies to probe the mechanisms that control cellular growth and to generate immortalized cell lines. Binding of T antigen to the Rb family of growth-regulatory proteins is n...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Sullivan, Christopher S., Cantalupo, Paul, Pipas, James M.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 2000
Assuntos:	Transcriptional Regulation
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86098/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938100/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6233-6243.2000
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