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Prothymosin Alpha Selectively Enhances Estrogen Receptor Transcriptional Activity by Interacting with a Repressor of Estrogen Receptor Activity

We find that prothymosin alpha (PTα) selectively enhances transcriptional activation by the estrogen receptor (ER) but not transcriptional activity of other nuclear hormone receptors. This selectivity for ER is explained by PTα interaction not with ER, but with a 37-kDa protein denoted REA, for repr...

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Udgivet i:Mol Cell Biol
Principais autores: Martini, Paolo G. V., Delage-Mourroux, Regis, Kraichely, Dennis M., Katzenellenbogen, Benita S.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86097/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10938099/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.17.6224-6232.2000
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