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Induction of Cell Cycle Progression and Acceleration of Apoptosis Are Two Separable Functions of c-Myc: Transrepression Correlates with Acceleration of Apoptosis

Analysis of amino-terminus mutants of c-Myc has allowed a systematic study of the interrelationship between Myc's ability to regulate transcription and its apoptotic, proliferative, and transforming functions. First, we have found that c-Myc-accelerated apoptosis does not directly correlate wit...

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Detalhes bibliográficos
Main Authors: Conzen, Suzanne D., Gottlob, Kathrin, Kandel, Eugene S., Khanduri, Pratibha, Wagner, Andrew J., O'Leary, Maura, Hay, Nissim
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86077/
https://ncbi.nlm.nih.gov/pubmed/10913183
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