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The Two Proteins Pat1p (Mrt1p) and Spb8p Interact In Vivo, Are Required for mRNA Decay, and Are Functionally Linked to Pab1p

We report here the characterization of a bypass suppressor of pab1Δ which leads to a fourfold stabilization of the unstable MFA2 mRNA. Cloning of the wild-type gene for that suppressor reveals that it is identical to PAT1 (YCR077c), a gene whose product was reported to interact with Top2p. PAT1 is n...

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Detalhes bibliográficos
Main Authors: Bonnerot, Claire, Boeck, Ronald, Lapeyre, Bruno
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86071/
https://ncbi.nlm.nih.gov/pubmed/10913177
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