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Identification of the Cytolinker Plectin as a Major Early In Vivo Substrate for Caspase 8 during CD95- and Tumor Necrosis Factor Receptor-Mediated Apoptosis

Caspase 8 plays an essential role in the execution of death receptor-mediated apoptosis. To determine the localization of endogenous caspase 8, we used a panel of subunit-specific anti-caspase 8 monoclonal antibodies in confocal immunofluorescence microscopy. In the human breast carcinoma cell line...

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Autori principali: Stegh, Alexander H., Herrmann, Harald, Lampel, Stefan, Weisenberger, Dieter, Andrä, Kerstin, Seper, Martin, Wiche, Gerhard, Krammer, Peter H., Peter, Marcus E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC86037/
https://ncbi.nlm.nih.gov/pubmed/10891503
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