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Poly(A) Polymerase Phosphorylation Is Dependent on Novel Interactions with Cyclins

We have previously shown that poly(A) polymerase (PAP) is negatively regulated by cyclin B-cdc2 kinase hyperphosphorylation in the M phase of the cell cycle. Here we show that cyclin B(1) binds PAP directly, and we demonstrate further that this interaction is mediated by a stretch of amino acids in...

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Bibliografiske detaljer
Main Authors: Bond, Gareth L., Prives, Carol, Manley, James L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2000
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85980/
https://ncbi.nlm.nih.gov/pubmed/10866687
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