Disruption of Myc-Tubulin Interaction by Hyperphosphorylation of c-Myc during Mitosis or by Constitutive Hyperphosphorylation of Mutant c-Myc in Burkitt's Lymphoma

Somatic mutations at Thr-58 of c-Myc have been detected in Burkitt's lymphoma (BL) tumors and have been shown to affect the transforming potential of the Myc oncoprotein. In addition, the N-terminal domain of c-Myc has been shown to interact with microtubules in vivo, and the binding of c-Myc to α-t...

Description complète

Détails bibliographiques

Publié dans:	Mol Cell Biol
Auteurs principaux:	Niklinski, Jacek, Claassen, Gisela, Meyers, Cheryl, Gregory, Mark A., Allegra, Carmen J., Kaye, Frederic J., Hann, Stephen R., Zajac-Kaye, Maria
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2000
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85977/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10866684/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.14.5276-5284.2000
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!