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Mechanism of Transcriptional Regulation by Methyl-CpG Binding Protein MBD1

MBD1 is a mammalian protein that binds symmetrically methylated CpG sequences and regulates gene expression in association with DNA methylation. This protein possesses a conserved sequence, named methyl-CpG binding domain (MBD), among a family of methyl-CpG binding proteins that mediate the biologic...

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Detalhes bibliográficos
Main Authors: Fujita, Naoyuki, Shimotake, Nobuya, Ohki, Izuru, Chiba, Tsutomu, Saya, Hideyuki, Shirakawa, Masahiro, Nakao, Mitsuyoshi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85960/
https://ncbi.nlm.nih.gov/pubmed/10866667
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