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Conservation and Function of a Potential Substrate-Binding Domain in the Yeast Clb5 B-Type Cyclin

Cyclin A contains a region implicated in binding to the p27 inhibitor and to substrates. There is strong evolutionary conservation of surface residues contributing to this region in many cyclins, including yeast B-type cyclins, despite the absence of a yeast p27 homolog. The yeast S-phase B-type cyc...

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Autors principals: Cross, Frederick R., Jacobson, Matthew D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC85916/
https://ncbi.nlm.nih.gov/pubmed/10848604
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