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Dominant Active Alleles of RIM101 (PRR2) Bypass the pH Restriction on Filamentation of Candida albicans

Morphological development of the fungal pathogen Candida albicans is profoundly affected by ambient pH. Acidic pH restricts growth to the yeast form, whereas neutral pH permits development of the filamentous form. Superimposed on the pH restriction is a temperature requirement of approximately 37°C...

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Bibliographic Details
Main Authors: El Barkani, Abdelmalic, Kurzai, Oliver, Fonzi, William A., Ramon, Ana, Porta, Amalia, Frosch, Matthias, Mühlschlegel, Fritz A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC85869/
https://ncbi.nlm.nih.gov/pubmed/10848590
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