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Transcription Factor Hepatocyte Nuclear Factor 6 Regulates Pancreatic Endocrine Cell Differentiation and Controls Expression of the Proendocrine Gene ngn3

Hepatocyte nuclear factor 6 (HNF-6) is the prototype of a new class of cut homeodomain transcription factors. During mouse development, HNF-6 is expressed in the epithelial cells that are precursors of the exocrine and endocrine pancreatic cells. We have investigated the role of HNF-6 in pancreas di...

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Autores principales: Jacquemin, Patrick, Durviaux, Serge M., Jensen, Jan, Godfraind, Catherine, Gradwohl, Gerard, Guillemot, François, Madsen, Ole D., Carmeliet, Peter, Dewerchin, Mieke, Collen, Désiré, Rousseau, Guy G., Lemaigre, Frédéric P.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC85812/
https://ncbi.nlm.nih.gov/pubmed/10825208
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