Hepatocyte-Specific Mutation Establishes Retinoid X Receptor α as a Heterodimeric Integrator of Multiple Physiological Processes in the Liver

A large number of physiological processes in the adult liver are regulated by nuclear receptors that require heterodimerization with retinoid X receptors (RXRs). In this study, we have used cre-mediated recombination to disrupt the mouse RXRα gene specifically in hepatocytes. Although such mice are...

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Detalhes bibliográficos
Main Authors: Wan, Yu-Jui Yvonne, An, Dahsing, Cai, Yan, Repa, Joyce J., Hung-Po Chen, Tim, Flores, Monica, Postic, Catherine, Magnuson, Mark A., Chen, Ju, Chien, Kenneth R., French, Samuel, Mangelsdorf, David J., Sucov, Henry M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Cell Growth and Development
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85811/
https://ncbi.nlm.nih.gov/pubmed/10825207
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