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Mad1 Function Is Regulated through Elements within the Carboxy Terminus

Myc and Mad are basic helix-loop-helix leucine zipper (bHLH-LZ) proteins that heterodimerize with Max to bind DNA and thereby influence the transcription of Myc-responsive genes. Myc-Max dimers transactivate whereas Mad-Max-mSin3 complexes repress Myc-mediated transcriptional activation. We have pre...

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Autors principals: Barrera-Hernandez, Gonzalo, Cultraro, Constance M., Pianetti, Stefania, Segal, Shoshana
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC85793/
https://ncbi.nlm.nih.gov/pubmed/10825189
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