Analysis of Fractalkine Receptor CX(3)CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

The seven-transmembrane receptor CX(3)CR1 is a specific receptor for the novel CX(3)C chemokine fractalkine (FKN) (neurotactin). In vitro data suggest that membrane anchoring of FKN, and the existence of a shed, soluble FKN isoform allow for both adhesive and chemoattractive properties. Expression o...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Jung, Steffen, Aliberti, Julio, Graemmel, Petra, Sunshine, Mary Jean, Kreutzberg, Georg W., Sher, Alan, Littman, Dan R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85780/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10805752/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.11.4106-4114.2000
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