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Mutational Analysis of Mammalian Translation Initiation Factor 5 (eIF5): Role of Interaction between the β Subunit of eIF2 and eIF5 in eIF5 Function In Vitro and In Vivo

Eukaryotic translation initiation factor 5 (eIF5) interacts with the 40S initiation complex (40S–eIF3–AUG–Met-tRNA(f)–eIF2–GTP) to promote the hydrolysis of ribosome-bound GTP. eIF5 also forms a complex with eIF2 by interacting with the β subunit of eIF2. In this work, we have used a mutational appr...

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Bibliografiska uppgifter
Huvudupphovsmän: Das, Supratik, Maitra, Umadas
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC85746/
https://ncbi.nlm.nih.gov/pubmed/10805737
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