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Analysis by Multiplex PCR of the Physical Status of Human Papillomavirus Type 16 DNA in Cervical Cancers

Integration of human papillomavirus (HPV) DNA occurs early in cancer development and is an important event in malignant transformation of cervical cancer. Integration of HPVs preferentially disrupts or deletes the E2 open reading frame, which results in the loss of its expression. The preferential d...

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Autors principals: Yoshinouchi, Mitsuo, Hongo, Atsushi, Nakamura, Keichiro, Kodama, Junichi, Itoh, Sachio, Sakai, Hiroyuki, Kudo, Takafumi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC85682/
https://ncbi.nlm.nih.gov/pubmed/10523544
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