Deletion of the PAT1 Gene Affects Translation Initiation and Suppresses a PAB1 Gene Deletion in Yeast

The yeast poly(A) binding protein Pab1p mediates the interactions between the 5′ cap structure and the 3′ poly(A) tail of mRNA, whose structures synergistically activate translation in vivo and in vitro. We found that deletion of the PAT1 (YCR077c) gene suppresses a PAB1 gene deletion and that Pat1p...

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Bibliographic Details
Main Authors: Wyers, Françoise, Minet, Michèle, Dufour, Marie Elisabeth, Vo, Le Thuy Anh, Lacroute, François
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC85646/
https://ncbi.nlm.nih.gov/pubmed/10779343
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