Deficient Gene Expression in Protein Kinase Inhibitor α Null Mutant Mice

Protein kinase inhibitor (PKI) is a potent endogenous inhibitor of the cyclic AMP (cAMP)-dependent protein kinase (PKA). It functions by binding the free catalytic (C) subunit with a high affinity and is also known to export nuclear C subunit to the cytoplasm. The significance of these actions with...

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Detalhes bibliográficos
Main Authors: Gangolli, Esha A., Belyamani, Mouna, Muchinsky, Sara, Narula, Anita, Burton, Kimberly A., McKnight, G. Stanley, Uhler, Michael D., Idzerda, Rejean L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Mammalian Genetic Models with Minimal or Complex Phenotypes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85637/
https://ncbi.nlm.nih.gov/pubmed/10779334
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