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TLS-ERG Leukemia Fusion Protein Inhibits RNA Splicing Mediated by Serine-Arginine Proteins

The translocation liposarcoma (TLS) gene is fused to the ETS-related gene (ERG) in human myeloid leukemia, resulting in the generation of a TLS-ERG protein. We demonstrate that both TLS and the TLS-ERG leukemia fusion protein bind to RNA polymerase II through the TLS N-terminal domain, which is reta...

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Bibliografski detalji
Glavni autori: Yang, Liu, Embree, Lisa J., Hickstein, Dennis D.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC85627/
https://ncbi.nlm.nih.gov/pubmed/10779324
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