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17β-Estradiol Inhibits Apoptosis in MCF-7 Cells, Inducing bcl-2 Expression via Two Estrogen-Responsive Elements Present in the Coding Sequence

We have found that 17β-estradiol induces bcl-2 transcription in human breast cancer MCF-7 cells. To identify cis-acting elements involved in this regulation, we have analyzed hormone responsiveness of transiently transfected reporter constructs containing the bcl-2 major promoter (P(1)). Hormone ind...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Perillo, Bruno, Sasso, Annarita, Abbondanza, Ciro, Palumbo, Giuseppe
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2000
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC85519/
https://ncbi.nlm.nih.gov/pubmed/10733592
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