The DRIP Complex and SRC-1/p160 Coactivators Share Similar Nuclear Receptor Binding Determinants but Constitute Functionally Distinct Complexes

Transcriptional activation requires both access to DNA assembled as chromatin and functional contact with components of the basal transcription machinery. Using the hormone-bound vitamin D(3) receptor (VDR) ligand binding domain (LBD) as an affinity matrix, we previously identified a novel multisubu...

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Main Authors: Rachez, Christophe, Gamble, Matthew, Chang, Chao-Pei Betty, Atkins, G. Brandon, Lazar, Mitchell A., Freedman, Leonard P.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Transcriptional Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC85487/
https://ncbi.nlm.nih.gov/pubmed/10733574
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