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Nedd8 Modification of Cul-1 Activates SCF(β(TrCP))-Dependent Ubiquitination of IκBα
Regulation of NF-κB occurs through phosphorylation-dependent ubiquitination of IκBα, which is degraded by the 26S proteasome. Recent studies have shown that ubiquitination of IκBα is carried out by a ubiquitin-ligase enzyme complex called SCF(β(TrCP)). Here we show that Nedd8 modification of the Cul...
Shranjeno v:
| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Society for Microbiology
2000
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC85397/ https://ncbi.nlm.nih.gov/pubmed/10713156 |
| Oznake: |
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