Nedd8 Modification of Cul-1 Activates SCF(β(TrCP))-Dependent Ubiquitination of IκBα
Regulation of NF-κB occurs through phosphorylation-dependent ubiquitination of IκBα, which is degraded by the 26S proteasome. Recent studies have shown that ubiquitination of IκBα is carried out by a ubiquitin-ligase enzyme complex called SCF(β(TrCP)). Here we show that Nedd8 modification of the Cul...
Gorde:
| Argitaratua izan da: | Mol Cell Biol |
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| Egile Nagusiak: | , , , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Taylor & Francis
2000
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85397/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10713156/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.7.2326-2333.2000 |
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