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The BIR Motifs Mediate Dominant Interference and Oligomerization of Inhibitor of Apoptosis Op-IAP

The defining structural motif of the inhibitor of apoptosis (iap) protein family is the BIR (baculovirus iap repeat), a highly conserved zinc coordination domain of ∼70 residues. Although the BIR is required for inhibitor-of-apoptosis (IAP) function, including caspase inhibition, its molecular role...

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Pubblicato in:Mol Cell Biol
Autori principali: Hozak, Rebecca R., Manji, Gulam A., Friesen, Paul D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85372/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10669762/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.5.1877-1885.2000
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