Transient Expression of Cellular Polypyrimidine-Tract Binding Protein Stimulates Cap-Independent Translation Directed by Both Picornaviral and Flaviviral Internal Ribosome Entry Sites In Vivo

The regulation of cap-independent translation directed by the internal ribosome entry sites (IRESs) present in some viral and cellular RNAs is poorly understood. Polypyrimidine-tract binding protein (PTB) binds specifically to several viral IRESs. IRES-directed translation may be reduced in cell-fre...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Gosert, Rainer, Chang, Ki Ha, Rijnbrand, Rene, Yi, MinKyung, Sangar, David V., Lemon, Stanley M.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Gene Expression
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85342/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10669736/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.5.1583-1595.2000
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