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Mutations in the rpoB Gene of Rifampin-Resistant Mycobacterium tuberculosis Strains Isolated Mostly in Asian Countries and Their Rapid Detection by Line Probe Assay

Mutations in the rpoB gene of 90 rifampin-resistant Mycobacterium tuberculosis isolates mostly from Asian countries were analyzed. Ten distinct single-nucleotide substitutions were found among the isolates by automated sequencing. A 3-nucleotide insertion was found in two isolates, and no mutation w...

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Библиографические подробности
Главные авторы: Hirano, Kazue, Abe, Chiyoji, Takahashi, Mitsuyoshi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 1999
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC85308/
https://ncbi.nlm.nih.gov/pubmed/10405418
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