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The p21(WAF1/CIP1) Promoter Is Methylated in Rat-1 Cells: Stable Restoration of p53-Dependent p21(WAF1/CIP1) Expression after Transfection of a Genomic Clone Containing the p21(WAF1/CIP1) Gene

Rat-1 cells are used in many studies on transformation, cell cycle, and apoptosis. Whereas UV treatment of Rat-1 cells results in apoptosis, X-ray treatment does not induce either apoptosis or a cell cycle block. X-ray treatment of Rat-1 cells results in both an increase of p53 protein and expressio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Allan, Lindsey A., Duhig, Trevor, Read, Moira, Fried, Mike
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC85267/
https://ncbi.nlm.nih.gov/pubmed/10648615
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