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Orphan Receptor COUP-TF Is Required for Induction of Retinoic Acid Receptor β, Growth Inhibition, and Apoptosis by Retinoic Acid in Cancer Cells

Retinoic acid receptor β (RARβ) plays a critical role in mediating the anticancer effects of retinoids. Expression of RARβ is highly induced by retinoic acid (RA) through a RA response element (βRARE) that is activated by heterodimers of RARs and retinoid X receptors (RXRs). However, RARβ induction...

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Autori principali: Lin, Bingzhen, Chen, Guo-quan, Xiao, Dongmei, Kolluri, Siva Kumar, Cao, Xihua, Su, Hong, Zhang, Xiao-kun
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2000
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC85213/
https://ncbi.nlm.nih.gov/pubmed/10629053
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