HuR Regulates p21 mRNA Stabilization by UV Light

Expression of the cyclin-dependent kinase inhibitor p21 is highly induced by many stresses, including exposure to short-wavelength UV light (UVC), which increases p21 mRNA stability. Investigation into the mechanisms underlying this stabilization process revealed that proteins present in cytoplasmic...

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Autors principals: Wang, Wengong, Furneaux, Henry, Cheng, Huiming, Caldwell, M. Craig, Hutter, Dorothy, Liu, Yusen, Holbrook, Nikki, Gorospe, Myriam
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC85192/
https://ncbi.nlm.nih.gov/pubmed/10629032
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