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A GATA Box in the GATA-1 Gene Hematopoietic Enhancer Is a Critical Element in the Network of GATA Factors and Sites That Regulate This Gene

A region located at kbp −3.9 to −2.6 5′ to the first hematopoietic exon of the GATA-1 gene is necessary to recapitulate gene expression in both the primitive and definitive erythroid lineages. In transfection analyses, this region activated reporter gene expression from an artificial promoter in a p...

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Hlavní autoři: Nishimura, Shigeko, Takahashi, Satoru, Kuroha, Takashi, Suwabe, Naruyoshi, Nagasawa, Toshiro, Trainor, Cecelia, Yamamoto, Masayuki
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC85182/
https://ncbi.nlm.nih.gov/pubmed/10611250
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