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A Nuclear 3′-5′ Exonuclease Involved in mRNA Degradation Interacts with Poly(A) Polymerase and the hnRNA Protein Npl3p

Inactivation of poly(A) polymerase (encoded by PAP1) in Saccharomyces cerevisiae cells carrying the temperature-sensitive, lethal pap1-1 mutation results in reduced levels of poly(A)(+) mRNAs. Genetic selection for suppressors of pap1-1 yielded two recessive, cold-sensitive alleles of the gene RRP6....

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Udgivet i:Mol Cell Biol
Principais autores: Burkard, Karina T. D., Butler, J. Scott
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Gene Expression
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85144/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10611239/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.2.604-616.2000
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