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Borrelia burgdorferi in Tick Cell Culture Modulates Expression of Outer Surface Proteins A and C in Response to Temperature

The Lyme disease spirochete Borrelia burgdorferi sensu stricto downregulates outer surface protein A (OspA) and upregulates outer surface protein C (OspC) during tick feeding. The switching of these proteins correlates with increased spirochetal infectivity for the mammal. We examined the effect of...

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Main Authors: Obonyo, Marygorret, Munderloh, Ulrike G., Fingerle, Volker, Wilske, Bettina, Kurtti, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85101/
https://ncbi.nlm.nih.gov/pubmed/10364575
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