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Role of Apoptosis Signal-Regulating Kinase in Regulation of the c-Jun N-Terminal Kinase Pathway and Apoptosis in Sympathetic Neurons

We have previously shown that nerve growth factor (NGF) withdrawal-induced death requires the activity of the small GTP-binding protein Cdc42 and that overexpression of an active form of Cdc42 is sufficient to mediate neuronal apoptosis via activation of the c-Jun pathway. Recently, a new mitogen-ac...

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Hlavní autoři: Kanamoto, Takashi, Mota, Monica, Takeda, Kohsuke, Rubin, Lee L., Miyazono, Kohei, Ichijo, Hidenori, Bazenet, Chantal E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC85075/
https://ncbi.nlm.nih.gov/pubmed/10594022
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