Scanning Mutagenesis of Mcm1: Residues Required for DNA Binding, DNA Bending, and Transcriptional Activation by a MADS-Box Protein

MCM1 is an essential gene in the yeast Saccharomyces cerevisiae and is a member of the MADS-box family of transcriptional regulatory factors. To understand the nature of the protein-DNA interactions of this class of proteins, we have made a series of alanine substitutions in the DNA-binding domain o...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Acton, Thomas B., Mead, Janet, Steiner, Andrew M., Vershon, Andrew K.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2000
Schlagworte:	Transcriptional Regulation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85026/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10594003/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.1.1-11.2000
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