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Saccharomyces cerevisiae RNase H(35) Functions in RNA Primer Removal during Lagging-Strand DNA Synthesis, Most Efficiently in Cooperation with Rad27 Nuclease

Correct removal of RNA primers of Okazaki fragments during lagging-strand DNA synthesis is a critical process for the maintenance of genome integrity. Disturbance of this process has severe mutagenic consequences and could contribute to the development of cancer. The role of the mammalian nucleases...

詳細記述

保存先:
書誌詳細
主要な著者: Qiu, Junzhuan, Qian, Ying, Frank, Peter, Wintersberger, Ulrike, Shen, Binghui
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC84926/
https://ncbi.nlm.nih.gov/pubmed/10567561
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