Saccharomyces cerevisiae RNase H(35) Functions in RNA Primer Removal during Lagging-Strand DNA Synthesis, Most Efficiently in Cooperation with Rad27 Nuclease

Correct removal of RNA primers of Okazaki fragments during lagging-strand DNA synthesis is a critical process for the maintenance of genome integrity. Disturbance of this process has severe mutagenic consequences and could contribute to the development of cancer. The role of the mammalian nucleases...

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Bibliographic Details
Main Authors: Qiu, Junzhuan, Qian, Ying, Frank, Peter, Wintersberger, Ulrike, Shen, Binghui
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
DNA Dynamics and Chromosome Structure
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC84926/
https://ncbi.nlm.nih.gov/pubmed/10567561
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