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Mismatch Repair Processing of Carcinogen-DNA Adducts Triggers Apoptosis

The DNA mismatch repair pathway is well known for its role in correcting biosynthetic errors of DNA replication. We report here a novel role for mismatch repair in signaling programmed cell death in response to DNA damage induced by chemical carcinogens. Cells proficient in mismatch repair were high...

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Bibliografiska uppgifter
Huvudupphovsmän: Wu, Jianxin, Gu, Liya, Wang, Huixian, Geacintov, Nicholas E., Li, Guo-Min
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 1999
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC84913/
https://ncbi.nlm.nih.gov/pubmed/10567554
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