Evidence for Distinct Substrate Specificities of Importin α Family Members in Nuclear Protein Import

Importin α plays a pivotal role in the classical nuclear protein import pathway. Importin α shuttles between nucleus and cytoplasm, binds nuclear localization signal-bearing proteins, and functions as an adapter to access the importin β-dependent import pathway. In contrast to what is found for impo...

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Main Authors: Köhler, Matthias, Speck, Christian, Christiansen, Marret, Bischoff, F. Ralf, Prehn, Siegfried, Haller, Hermann, Görlich, Dirk, Hartmann, Enno
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 1999
Fag:
Nucleocytoplasmic Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84838/
https://ncbi.nlm.nih.gov/pubmed/10523667
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