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RelB Modulation of IκBα Stability as a Mechanism of Transcription Suppression of Interleukin-1α (IL-1α), IL-1β, and Tumor Necrosis Factor Alpha in Fibroblasts

Members of the NF-κB/RelB family of transcription factors play important roles in the regulation of inflammatory and immune responses. RelB, a member of this family, has been characterized as a transcription activator and is involved in the constitutive NF-κB activity in lymphoid tissues. However, i...

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Udgivet i:Mol Cell Biol
Principais autores: Xia, Yiyang, Chen, Shizhong, Wang, Yibin, Mackman, Nigel, Ku, George, Lo, David, Feng, Lili
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84809/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10523657/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.11.7688
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