The Mre11-Rad50-Xrs2 Protein Complex Facilitates Homologous Recombination-Based Double-Strand Break Repair in Saccharomyces cerevisiae

Saccharomyces cerevisiae mre11Δ mutants are profoundly deficient in double-strand break (DSB) repair, indicating that the Mre11-Rad50-Xrs2 protein complex plays a central role in the cellular response to DNA DSBs. In this study, we examined the role of the complex in homologous recombination, the pr...

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Autors principals: Bressan, Debra A., Baxter, Bonnie K., Petrini, John H. J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1999
Matèries:
DNA Dynamics and Chromosome Structure
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC84807/
https://ncbi.nlm.nih.gov/pubmed/10523656
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