Mutations in VPS16 and MRT1 Stabilize mRNAs by Activating an Inhibitor of the Decapping Enzyme

Decapping is a rate-limiting step in the decay of many yeast mRNAs; the activity of the decapping enzyme therefore plays a significant role in determining RNA stability. Using an in vitro decapping assay, we have identified a factor, Vps16p, that regulates the activity of the yeast decapping enzyme,...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Zhang, Shuang, Williams, Carol J., Hagan, Kevin, Peltz, Stuart W.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1999
Soggetti:	Gene Expression
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84771/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10523645/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.11.7568
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