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Separation-of-Function Mutations in Saccharomyces cerevisiae MSH2 That Confer Mismatch Repair Defects but Do Not Affect Nonhomologous-Tail Removal during Recombination

Yeast Msh2p forms complexes with Msh3p and Msh6p to repair DNA mispairs that arise during DNA replication. In addition to their role in mismatch repair (MMR), the MSH2 and MSH3 gene products are required to remove 3′ nonhomologous DNA tails during genetic recombination. The mismatch repair genes MSH...

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Détails bibliographiques
Auteurs principaux: Studamire, Barbara, Price, Gavrielle, Sugawara, Neal, Haber, James E., Alani, Eric
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1999
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC84769/
https://ncbi.nlm.nih.gov/pubmed/10523644
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