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De Novo Synthesis of Sphingolipids Is Required for Cell Survival by Down-Regulating c-Jun N-Terminal Kinase in Drosophila Imaginal Discs

Mitogen-activated protein kinase (MAPK) is a conserved eukaryotic signaling factor that mediates various signals, cumulating in the activation of transcription factors. Extracellular signal-regulated kinase (ERK), a MAPK, is activated through phosphorylation by the kinase MAPK/ERK kinase (MEK). To e...

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Main Authors: Adachi-Yamada, Takashi, Gotoh, Tomokazu, Sugimura, Isamu, Tateno, Minoru, Nishida, Yasuyoshi, Onuki, Tomoya, Date, Hideyuki
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC84720/
https://ncbi.nlm.nih.gov/pubmed/10490662
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