Interacting Regions in Stat3 and c-Jun That Participate in Cooperative Transcriptional Activation

Independent but closely spaced DNA binding sites for Stat3 and c-Jun are required for maximal enhancer function in a number of genes, including the gene encoding the interleukin-6 (IL-6)-induced acute-phase response protein, α(2)-macroglobulin. In addition, a physical interaction of Stat3 with c-Jun...

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Bibliographic Details
Main Authors: Zhang, Xiaokui, Wrzeszczynska, Melissa H., Horvath, Curt M., Darnell, James E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1999
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC84707/
https://ncbi.nlm.nih.gov/pubmed/10490649
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