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hnRNP U Inhibits Carboxy-Terminal Domain Phosphorylation by TFIIH and Represses RNA Polymerase II Elongation

This study describes a potential new function of hnRNP U as an RNA polymerase (Pol II) elongation inhibitor. We demonstrated that a subfraction of human hnRNP U is associated with the Pol II holoenzyme in vivo and as such recruited to the promoter as part of the preinitiation complex. hnRNP U, howev...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Kim, Myung K., Nikodem, Vera M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84680/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10490622/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.10.6833
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